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¹ Atatürk Üniversitesi, Su Ürünleri Fakültesi, Yetiştiricilik Bölümü, Ankara DOI : 10.17693/yunusae.vi.304127 Viewed : 4070 - Downloaded : 1856 In the present study on the toxic effects of alpha-cypermethrin, on rainbow trout were subjected to chronic administration with three different concentrations. At the end of application, blood parameters were performed. After exposure, hematological parameters such as hemoglobin, leucocyte, thrombocyte, MCV, MCH, and MCHC were significantly influenced by treatment (p<0.01), while hematocrit, sedimentation and erythrocyte were not significantly affected (p>0.05). In the light of these results, it is thought that Hematology parameters will be helpful in predicting disease and Alpha cypermethrin can create a toxic effect for living things in the aquatic ecosystem. Keywords : Rainbow trout, hematology, alpha-cypermethrin